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Fatal Pulmonary Embolism: Hystological Analysis
In general, the structure resembles
that of the adrenal cortex. Individual
cells are poorly defined, with a
vacuolated or granular pink cytoplasm.
Nuclei are heavily stained and
show fine chromatin reticulation.
They vary considerably in size and shape.
Giant nuclei are frequent usually
in mononuclear but occasionally
in multi-nucleated cells.
Vascular channels are scanty,
mitosis are infrequent, there is much
necrosis, and decalcification in
the necrotic areas is common.
Much fat present. The material gives
a strongly positive fuchsinophil reaction.
The appearance are those of a
malignant tumor of the adrenal cortex